The area of client needs related to administering acyclovir is which?

• A. Immunologic Safety
• B. Health Promotion and Maintenance
• C. Physiologic Integrity
• D. Safety and Infection Control

Answer: (C)

The main concept being tested is how medications interact with the body and how nurses protect physiologic function during drug therapy. Administering acyclovir requires understanding pharmacology, dosing, and monitoring for adverse effects to keep the body's systems stable. In pediatrics, this includes ensuring accurate dosing, watching for signs of nephrotoxicity or CNS effects, and monitoring kidney function (urine output, labs) and hydration—especially with IV administration where the risk of infusion-related complications or crystallization exists. These considerations are all about maintaining physiologic integrity—safely delivering pharmacologic therapy while preventing harm to the body's organs and processes. Other domains focus more on immune function, health promotion, or safety/infection control, but the core nursing responsibilities around drug effects, dosing, and physiological monitoring align best with physiologic integrity.